Lancet March 2026 The effectiveness of HPV vaccination against invasive cervical cancer and related precancerous lesions: a multinational target trial emulation study

This Week In Medicine · Mar 17, 2026 · 21m

By analyzing extensive healthcare data from the United Kingdom, Spain, and Norway, this study evaluates how well HPV vaccination programs protect young women against serious cervical disease over a fifteen-year period. Researchers utilized a target trial emulation to compare health outcomes between vaccinated and unvaccinated individuals, specifically focusing on the prevention of high-grade precancerous lesions and surgical interventions. The findings demonstrate a significant reduction in these risks, confirming that the vaccines remain a highly effective preventative measure in real-world…