Lancet July 2026 Temporal changes in cortisol secretion and their association with long-term outcomes in benign adrenal incidentalomas: a retrospective cohort study.

This Week In Medicine · Jul 8, 2026 · 1m

This study investigates the long-term health implications of mild autonomous cortisol secretion (MACS) in patients who have discovered unexpected, non-cancerous growths on their adrenal glands. By tracking hormone levels over several years, researchers found that nearly a quarter of patients experience fluctuating cortisol results, suggesting that a single test may not capture a person's full health profile. The data reveals that individuals with persistently elevated cortisol levels face a higher risk of worsening hypertension and a greater overall cardiometabolic burden compared to those…