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Leaky Gut: Real Biology vs. Internet Hype
Leaky gut" means something very specific in gastroenterology and something very different on wellness blogs. This episode unpacks the actual biology of intestinal permeability — the tight junction proteins, the paracellular pathway, and the gut-associated lymphoid tissue — then examines where the evidence actually lands. We cover the well-established connections to Crohn's disease and celiac, the plausible but unproven links to conditions like type 1 diabetes and NAFLD, and the shaky foundations of commercial testing like IgG panels and serum zonulin assays. If you've ever wondered whether…
The skinny
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