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JAMA February 2026 Treatment for Brain Metastases With Stereotactic Radiation vs Hippocampal-Avoidance Whole Brain Radiation
This clinical study investigated the most effective way to manage multiple brain metastases by comparing highly targeted stereotactic radiationagainst a broader approach that treats the entire brain while protecting the hippocampus. By measuring how cancer treatments affect a patient's symptom severity and daily functioning, researchers sought to identify which method preserves a higher quality of life for those with five to twenty tumors. The results demonstrated that the localized approach significantly outperformed the whole-brain method, leading to a meaningful reduction in…
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