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From Prozac to Plasticity: The New Science of Depression
In this episode, Herman and Corn dive deep into the evolving world of psychopharmacology, moving beyond the outdated "chemical imbalance" theory that has dominated the field for decades. They discuss why traditional SSRIs often fall short and explore the next generation of treatments, including multimodal antidepressants like Trintellix and the rapid-acting potential of NMDA modulators like Auvelity. The conversation also covers the revolutionary shift toward neuroplasticity, the promising but complex landscape of psychedelic-assisted therapy, and the emerging role of the gut-brain axis in…
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