Methylation vs. IEMs: Untangling the Confusion

Logosofia no Dia a Dia · Apr 25, 2026 · 25m

Methylation is often touted as a root cause of disease, but the science is far more nuanced. This episode cuts through the wellness industry hype to explain what methylation actually is—a simple chemical tag that regulates gene expression. We then untangle it from Inborn Errors of Metabolism (IEMs), which are rare, severe genetic diseases. Discover the critical difference between common MTHFR gene variants and life-threatening remethylation disorders, and explore the fascinating new research on how metabolic disturbances can secondarily alter our epigenome. Episode 2419 —…