Why Depression Drains Your Energy

My Weird Prompts · Oct 1, 2026 · 24m

Daniel wrote in about a friend with seasonal affective disorder, and asked a question that turns out to be two questions: how do light and mood actually connect, and why does non-seasonal depression drain energy at all? This episode traces the light pathway — from the intrinsically photosensitive retinal ganglion cells that don't help you see, to the contested question of whether light moves your circadian clock or acts on mood circuitry directly. Then it turns to the harder half: a condition where fatigue shows up in over ninety percent of patients, where reward processing and inflammation…