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4 High-Yield Cannabis Pearls Every Mental Health Provider Should Know · Pearls and Prep

• 0:00
  Foreign.
• 0:06
  Welcome
• 0:07
  back,
• 0:07
  my
• 0:07
  friends,
• 0:07
  to
• 0:08
  another
• 0:08
  episode
• 0:08
  of
• 0:09
  Pearls
• 0:09
  and
• 0:09
  Prep.
• 0:10
  Today
• 0:10
  is
• 0:11
  a
• 0:11
  doozy.
• 0:12
  I'm
• 0:13
  very
• 0:13
  excited
• 0:13
  for
• 0:14
  this
• 0:14
  one
• 0:14
  because
• 0:15
  it
• 0:15
  took
• 0:15
  me
• 0:15
  a
• 0:16
  long
• 0:16
  time
• 0:16
  to
• 0:16
  really
• 0:17
  wrap
• 0:17
  my
• 0:17
  head
• 0:17
  around
• 0:18
  the
• 0:18
  topic.
• 0:18
  We're
• 0:19
  going
• 0:19
  to
• 0:19
  talk
• 0:19
  about
• 0:20
  cannabis
• 0:21
  use,
• 0:21
  and
• 0:22
  we
• 0:22
  have
• 0:22
  four
• 0:23
  really
• 0:23
  good
• 0:24
  pearls
• 0:25
  for
• 0:25
  you
• 0:26
  to
• 0:26
  think
• 0:26
  about
• 0:27
  as
• 0:27
  we
• 0:27
  talk
• 0:27
  about
• 0:28
  cannabis
• 0:29
  use
• 0:29
  with
• 0:29
  our
• 0:30
  patients.
• 0:30
  I
• 0:31
  think
• 0:31
  before
• 0:31
  we
• 0:32
  even
• 0:32
  delve
• 0:32
  too
• 0:33
  deeply
• 0:33
  into
• 0:33
  this,
• 0:34
  my
• 0:34
  first
• 0:35
  pearl
• 0:35
  has
• 0:35
  to
• 0:35
  do
• 0:36
  with
• 0:36
  the
• 0:36
  endocannabinoid
• 0:37
  system,
• 0:38
  because
• 0:38
  understanding
• 0:39
  the
• 0:39
  system
• 0:39
  or
• 0:40
  having
• 0:40
  a
• 0:40
  conceptual
• 0:41
  appreciation
• 0:41
  for
• 0:41
  the
• 0:42
  system
• 0:42
  is
• 0:43
  integral
• 0:43
  if
• 0:44
  we're
• 0:44
  going
• 0:44
  to
• 0:44
  go
• 0:44
  into
• 0:44
  the
• 0:45
  other
• 0:45
  three
• 0:45
  pearls.
• 0:46
  The
• 0:46
  endocannabinoid
• 0:47
  system
• 0:48
  is
• 0:48
  a
• 0:48
  way
• 0:48
  that
• 0:49
  neurotransmitters
• 0:50
  signal
• 0:51
  with
• 0:51
  each
• 0:51
  other
• 0:51
  to.
• 0:52
  To
• 0:52
  keep
• 0:52
  a
• 0:52
  balance
• 0:53
  within
• 0:53
  the
• 0:54
  system.
• 0:54
  Thc,
• 0:55
  particularly
• 0:56
  high
• 0:56
  potency
• 0:56
  thc,
• 0:58
  can
• 0:58
  actually
• 0:59
  mess
• 0:59
  with
• 0:59
  the
• 1:00
  system
• 1:00
  and
• 1:01
  throw
• 1:01
  it
• 1:01
  off
• 1:01
  balance.
• 1:02
  This
• 1:02
  master
• 1:03
  regulator
• 1:03
  of
• 1:04
  the
• 1:04
  endocannabinoid
• 1:05
  system
• 1:05
  doesn't
• 1:06
  work
• 1:06
  properly.
• 1:07
  It
• 1:07
  doesn't
• 1:07
  cool
• 1:07
  down
• 1:08
  excitatory
• 1:09
  neurotransmitters
• 1:10
  when
• 1:10
  it
• 1:10
  should.
• 1:11
  It
• 1:11
  does
• 1:12
  this
• 1:12
  through
• 1:13
  retrograde
• 1:14
  inhibition.
• 1:15
  You've
• 1:15
  probably
• 1:15
  read
• 1:15
  that
• 1:16
  when
• 1:16
  neurons
• 1:16
  communicate
• 1:17
  with
• 1:17
  each
• 1:17
  other
• 1:17
  and
• 1:18
  they
• 1:18
  fire
• 1:18
  and
• 1:18
  wire
• 1:19
  they
• 1:19
  with
• 1:19
  retrograde
• 1:20
  inhibition,
• 1:20
  a
• 1:21
  neuron
• 1:21
  fires
• 1:21
  back
• 1:22
  to
• 1:22
  the
• 1:22
  original
• 1:22
  neuron
• 1:23
  and
• 1:23
  says,
• 1:23
  hey,
• 1:23
  why
• 1:24
  don't
• 1:24
  you
• 1:24
  cool
• 1:24
  down
• 1:24
  a
• 1:25
  bit?
• 1:25
  Why
• 1:25
  don't
• 1:26
  you
• 1:26
  dampen
• 1:26
  your
• 1:27
  glutamate
• 1:27
  response
• 1:28
  a
• 1:28
  little
• 1:28
  bit?
• 1:29
  Um,
• 1:29
  it's
• 1:30
  too
• 1:30
  excitatory
• 1:31
  at
• 1:31
  this
• 1:31
  point.
• 1:31
  So
• 1:32
  that's
• 1:32
  kind
• 1:32
  of
• 1:32
  retrograde
• 1:33
  inhibition
• 1:33
  where
• 1:33
  cell
• 1:34
  signaling
• 1:34
  will
• 1:35
  go
• 1:35
  backwards
• 1:36
  to
• 1:36
  inform
• 1:37
  the
• 1:37
  system
• 1:37
  to
• 1:37
  cool
• 1:38
  down
• 1:38
  and
• 1:38
  regulate
• 1:39
  itself.
• 1:39
  These
• 1:39
  systems
• 1:40
  are
• 1:41
  really
• 1:41
  critical
• 1:41
  because
• 1:42
  they
• 1:42
  touch
• 1:42
  on
• 1:42
  mood
• 1:43
  and
• 1:43
  stress
• 1:44
  response
• 1:44
  and
• 1:44
  pain
• 1:45
  signaling
• 1:45
  and
• 1:45
  immune
• 1:46
  activity,
• 1:46
  metabolism,
• 1:47
  neuroprotection.
• 1:48
  So
• 1:49
  when
• 1:50
  folks
• 1:50
  abuse
• 1:51
  THC,
• 1:52
  high
• 1:53
  potency
• 1:54
  THC,
• 1:55
  that's
• 1:55
  10%
• 1:55
  or
• 1:56
  more.
• 1:56
  This
• 1:56
  whole
• 1:57
  system
• 1:58
  gets
• 1:58
  really
• 1:59
  out
• 1:59
  of
• 1:59
  whack.
• 1:59
  It's
• 2:00
  a
• 2:00
  master
• 2:00
  regulator
• 2:01
  system
• 2:02
  and
• 2:02
  a
• 2:02
  lot
• 2:03
  of
• 2:03
  our
• 2:03
  major
• 2:03
  brain
• 2:04
  neurotransmitters,
• 2:05
  gaba,
• 2:06
  glutamate,
• 2:06
  that
• 2:07
  control
• 2:07
  braking
• 2:08
  and
• 2:08
  excitation,
• 2:09
  in
• 2:09
  addition
• 2:10
  to
• 2:10
  dopamine,
• 2:10
  serotonin,
• 2:11
  norepinephrine,
• 2:12
  acetylcholine,
• 2:12
  which
• 2:12
  affect
• 2:13
  mood,
• 2:13
  motivation,
• 2:13
  focus,
• 2:14
  memory,
• 2:14
  and
• 2:14
  alertness.
• 2:15
  All
• 2:15
  these
• 2:16
  systems
• 2:16
  get
• 2:17
  really
• 2:18
  bogged
• 2:18
  down
• 2:18
  and
• 2:19
  confused
• 2:20
  and
• 2:20
  so.
• 2:21
  And
• 2:21
  that
• 2:21
  kind
• 2:21
  of
• 2:21
  leads
• 2:22
  into
• 2:22
  my
• 2:22
  other
• 2:22
  pearl
• 2:24
  a
• 2:24
  couple
• 2:24
  pearls
• 2:25
  from
• 2:25
  now.
• 2:25
  This
• 2:25
  is
• 2:26
  all
• 2:26
  going
• 2:26
  to
• 2:26
  kind
• 2:26
  of
• 2:26
  tie
• 2:26
  together
• 2:27
  in
• 2:27
  that
• 2:27
  Cannabis
• 2:28
  is
• 2:28
  kind
• 2:28
  of
• 2:29
  like
• 2:29
  mud.
• 2:29
  It
• 2:30
  muddies
• 2:30
  the
• 2:30
  waters
• 2:31
  in
• 2:32
  your
• 2:32
  diagnostic
• 2:33
  picture.
• 2:33
  And
• 2:34
  I
• 2:34
  didn't
• 2:34
  mean
• 2:34
  to
• 2:34
  give
• 2:34
  you
• 2:35
  that
• 2:35
  sneak
• 2:35
  peek,
• 2:35
  pearl,
• 2:36
  but
• 2:36
  I
• 2:37
  wanted
• 2:37
  you
• 2:37
  to
• 2:37
  first
• 2:37
  start
• 2:38
  with
• 2:38
  the
• 2:38
  overarching
• 2:39
  pearl.
• 2:39
  And
• 2:40
  pearl
• 2:40
  number
• 2:40
  one
• 2:40
  is
• 2:40
  the
• 2:41
  endocannabinoid
• 2:42
  system.
• 2:42
  Is
• 2:43
  not
• 2:43
  really
• 2:43
  a
• 2:43
  feel
• 2:44
  good
• 2:44
  system,
• 2:44
  but
• 2:44
  it's
• 2:45
  a
• 2:45
  system
• 2:45
  of
• 2:45
  balance.
• 2:46
  And
• 2:46
  its
• 2:47
  main
• 2:47
  job
• 2:47
  is
• 2:47
  to
• 2:47
  keep
• 2:48
  neurotransmitters
• 2:49
  from
• 2:49
  getting
• 2:49
  too
• 2:49
  loud
• 2:49
  or
• 2:50
  too
• 2:50
  quiet.
• 2:50
  It's
• 2:51
  a
• 2:51
  master
• 2:51
  regulator.
• 2:52
  And
• 2:52
  absolutely
• 2:53
  high
• 2:53
  potency
• 2:54
  THC
• 2:54
  can
• 2:55
  throw
• 2:55
  that
• 2:56
  to
• 2:56
  the
• 2:56
  wind
• 2:57
  and
• 2:57
  make
• 2:57
  your
• 2:57
  life
• 2:58
  and
• 2:58
  your
• 2:58
  patient's
• 2:59
  life
• 2:59
  a
• 2:59
  lot
• 3:00
  more
• 3:00
  difficult.
• 3:01
  High
• 3:02
  potency
• 3:02
  THC
• 3:03
  will
• 3:03
  saturate
• 3:03
  these
• 3:04
  cannabinoid
• 3:05
  receptors,
• 3:05
  these
• 3:05
  CB1
• 3:06
  receptors.
• 3:07
  Through
• 3:07
  time,
• 3:08
  the
• 3:08
  CB1
• 3:09
  receptors
• 3:09
  will
• 3:09
  downregulate.
• 3:10
  It
• 3:11
  just
• 3:11
  really
• 3:13
  messes
• 3:13
  with
• 3:13
  your
• 3:14
  household
• 3:15
  thermostat,
• 3:15
  the
• 3:15
  whole
• 3:16
  regulatory
• 3:16
  system.
• 3:17
  It's
• 3:17
  kind
• 3:17
  of
• 3:17
  like
• 3:17
  if
• 3:18
  you
• 3:18
  put
• 3:18
  the
• 3:18
  heat
• 3:18
  all
• 3:19
  the
• 3:19
  way
• 3:19
  on
• 3:19
  full
• 3:19
  blast
• 3:20
  and
• 3:20
  then
• 3:20
  you
• 3:20
  made
• 3:21
  it
• 3:21
  as
• 3:21
  cold
• 3:21
  as
• 3:21
  possible
• 3:22
  with
• 3:22
  the
• 3:22
  ac,
• 3:23
  and
• 3:23
  pretty
• 3:23
  soon
• 3:23
  your
• 3:23
  thermostat's
• 3:24
  like,
• 3:24
  wait,
• 3:24
  what
• 3:24
  are
• 3:25
  we
• 3:25
  doing
• 3:25
  here?
• 3:25
  What
• 3:26
  temperature
• 3:26
  are
• 3:26
  we
• 3:26
  supposed
• 3:27
  to
• 3:27
  set?
• 3:27
  What
• 3:27
  are
• 3:27
  we
• 3:27
  supposed
• 3:28
  to
• 3:28
  do?
• 3:28
  But
• 3:28
  imagine
• 3:29
  that
• 3:29
  thermostat
• 3:29
  system
• 3:30
  governs
• 3:31
  and
• 3:31
  modulates
• 3:32
  so
• 3:32
  many
• 3:33
  other
• 3:34
  aspects
• 3:34
  of
• 3:35
  a
• 3:35
  person's
• 3:36
  physiological
• 3:37
  or
• 3:37
  mental
• 3:37
  health.
• 3:37
  We're
• 3:37
  talking
• 3:38
  about
• 3:38
  the
• 3:38
  inflammatory
• 3:39
  response,
• 3:39
  neuroprotection,
• 3:40
  metabolism,
• 3:41
  stress,
• 3:42
  anxiety,
• 3:43
  psychosis,
• 3:43
  pain.
• 3:44
  That's
• 3:45
  pretty
• 3:45
  much
• 3:45
  everything
• 3:45
  you're
• 3:46
  ever
• 3:46
  going
• 3:46
  to
• 3:46
  see
• 3:46
  in
• 3:46
  your
• 3:47
  clinic.
• 3:47
  So
• 3:48
  I
• 3:48
  urge
• 3:49
  all
• 3:49
  of
• 3:49
  you
• 3:49
  to
• 3:50
  dive
• 3:51
  a
• 3:51
  little
• 3:51
  deeper
• 3:51
  into
• 3:52
  the
• 3:52
  endocannabinoid
• 3:53
  system.
• 3:53
  See
• 3:53
  how
• 3:54
  it
• 3:54
  works.
• 3:54
  The
• 3:55
  retrograde
• 3:56
  inhibition
• 3:57
  and
• 3:57
  signaling
• 3:57
  is
• 3:58
  actually
• 3:58
  very
• 3:58
  interesting.
• 3:59
  It's
• 3:59
  a
• 3:59
  very
• 3:59
  elegant
• 4:00
  system,
• 4:00
  how
• 4:01
  our
• 4:01
  neurotransmitters
• 4:02
  communicate
• 4:02
  with
• 4:02
  each
• 4:02
  other
• 4:03
  to
• 4:03
  make
• 4:03
  sure
• 4:04
  that
• 4:04
  the
• 4:04
  right
• 4:04
  amount
• 4:05
  is
• 4:05
  excreted
• 4:06
  at
• 4:06
  the
• 4:06
  right
• 4:06
  times
• 4:07
  and
• 4:07
  that
• 4:07
  some
• 4:08
  are
• 4:08
  dampened
• 4:09
  when
• 4:09
  they're
• 4:09
  too
• 4:09
  much.
• 4:10
  So
• 4:11
  definitely
• 4:11
  starting
• 4:12
  with
• 4:12
  the
• 4:12
  endocannabinoid
• 4:13
  pearl,
• 4:13
  I
• 4:13
  hope
• 4:13
  you
• 4:14
  appreciated
• 4:14
  that
• 4:15
  and
• 4:15
  you
• 4:15
  delve
• 4:15
  a
• 4:15
  little
• 4:16
  deeper
• 4:16
  into
• 4:16
  it
• 4:16
  because
• 4:16
  it's
• 4:17
  pretty
• 4:17
  cool.
• 4:17
  And
• 4:17
  if
• 4:17
  you
• 4:17
  understand
• 4:18
  it,
• 4:18
  you'll
• 4:18
  kind
• 4:18
  of
• 4:18
  get
• 4:19
  why
• 4:19
  high
• 4:20
  potency
• 4:20
  THC
• 4:21
  products
• 4:22
  are
• 4:22
  a
• 4:22
  little
• 4:22
  bit
• 4:23
  problematic.
• 4:23
  Without
• 4:24
  further
• 4:24
  ado,
• 4:25
  let's
• 4:25
  talk
• 4:25
  about
• 4:26
  pearl
• 4:26
  number
• 4:26
  two.
• 4:27
  My
• 4:27
  pearl
• 4:27
  number
• 4:28
  two
• 4:28
  is
• 4:28
  very
• 4:28
  simple.
• 4:29
  Always
• 4:29
  ask
• 4:29
  about
• 4:30
  potency
• 4:30
  of
• 4:31
  your
• 4:31
  THC
• 4:31
  products.
• 4:32
  It
• 4:33
  takes
• 4:33
  an
• 4:34
  encyclopedic
• 4:35
  memory
• 4:35
  to
• 4:36
  keep
• 4:36
  up
• 4:36
  with
• 4:36
  all
• 4:37
  of
• 4:37
  the
• 4:37
  different
• 4:37
  cannabis
• 4:38
  products
• 4:38
  out
• 4:38
  there
• 4:39
  and
• 4:39
  THC
• 4:39
  content
• 4:40
  and
• 4:40
  the
• 4:40
  different
• 4:40
  delivery
• 4:41
  systems
• 4:41
  of
• 4:42
  cannabis.
• 4:42
  But
• 4:42
  I
• 4:43
  think
• 4:43
  we
• 4:43
  could
• 4:43
  totally
• 4:43
  do
• 4:44
  an
• 4:44
  episode
• 4:45
  on
• 4:45
  all
• 4:45
  the
• 4:45
  different
• 4:45
  methods
• 4:46
  of
• 4:46
  THC
• 4:47
  consumption.
• 4:47
  But
• 4:48
  the
• 4:48
  pearl
• 4:48
  I
• 4:48
  want
• 4:48
  you
• 4:49
  to
• 4:49
  stick
• 4:49
  in
• 4:49
  your
• 4:50
  brains
• 4:50
  is
• 4:51
  to
• 4:51
  think
• 4:51
  about
• 4:51
  the
• 4:52
  potency.
• 4:52
  I
• 4:52
  want
• 4:52
  you
• 4:53
  to
• 4:53
  ask
• 4:53
  about
• 4:53
  the
• 4:53
  potency.
• 4:54
  And
• 4:54
  a
• 4:54
  lot
• 4:54
  of
• 4:54
  your
• 4:55
  patients,
• 4:55
  they're
• 4:55
  not
• 4:55
  going
• 4:55
  to
• 4:55
  necessarily
• 4:56
  know
• 4:56
  either,
• 4:57
  right?
• 4:57
  They're
• 4:57
  not
• 4:57
  going
• 4:57
  to
• 4:57
  be
• 4:58
  like,
• 4:58
  wow,
• 4:58
  the
• 4:58
  potency
• 4:58
  of
• 4:59
  the
• 4:59
  THC
• 4:59
  products,
• 5:00
  56%.
• 5:01
  But
• 5:01
  anything
• 5:01
  over
• 5:02
  10%
• 5:02
  is
• 5:02
  considered
• 5:03
  high
• 5:03
  potency
• 5:04
  and
• 5:04
  is
• 5:04
  associated
• 5:05
  with
• 5:05
  substantially
• 5:06
  increased
• 5:06
  risk
• 5:07
  psychiatrically
• 5:08
  compared
• 5:08
  to
• 5:08
  lower
• 5:09
  potency
• 5:09
  products.
• 5:10
  That's
• 5:10
  why
• 5:10
  you
• 5:11
  really
• 5:11
  want
• 5:11
  to
• 5:12
  ask.
• 5:12
  That's
• 5:13
  when
• 5:13
  you
• 5:13
  start
• 5:14
  to
• 5:14
  get
• 5:14
  a
• 5:14
  lot
• 5:15
  more
• 5:15
  suspicious
• 5:16
  about
• 5:17
  heavy
• 5:17
  duty
• 5:17
  symptoms
• 5:18
  that
• 5:18
  you
• 5:18
  need
• 5:19
  to
• 5:19
  know
• 5:19
  about,
• 5:19
  right?
• 5:20
  A
• 5:20
  high
• 5:20
  potency
• 5:21
  greater
• 5:21
  or
• 5:21
  equal
• 5:22
  to
• 5:22
  10%
• 5:22
  THC
• 5:23
  can
• 5:23
  mean
• 5:24
  the
• 5:24
  difference
• 5:25
  between
• 5:25
  a
• 5:26
  75%
• 5:27
  increase
• 5:27
  in
• 5:27
  psychotic
• 5:28
  like
• 5:28
  experiences,
• 5:30
  a
• 5:30
  65%
• 5:31
  increase
• 5:31
  in
• 5:32
  generalized
• 5:32
  anxiety
• 5:33
  disorder
• 5:33
  presentations,
• 5:35
  and
• 5:35
  a
• 5:36
  fourfold
• 5:36
  increase
• 5:37
  in
• 5:37
  developing
• 5:37
  cannabis
• 5:38
  use
• 5:38
  disorder,
• 5:39
  even
• 5:39
  after
• 5:39
  adjusting
• 5:40
  for
• 5:40
  frequency
• 5:41
  of
• 5:41
  use.
• 5:41
  These
• 5:42
  are
• 5:42
  big
• 5:42
  statistics,
• 5:43
  right?
• 5:43
  What
• 5:43
  this
• 5:43
  is
• 5:43
  saying
• 5:44
  is
• 5:45
  based
• 5:45
  on
• 5:45
  your
• 5:46
  THC
• 5:46
  potency,
• 5:48
  the
• 5:48
  kinds
• 5:49
  of
• 5:49
  diagnoses
• 5:50
  that
• 5:50
  you
• 5:50
  might
• 5:50
  see
• 5:51
  in
• 5:51
  your
• 5:51
  clinic
• 5:52
  are
• 5:52
  going
• 5:52
  to
• 5:52
  explode.
• 5:53
  And
• 5:53
  again,
• 5:54
  they're
• 5:54
  going
• 5:54
  to
• 5:54
  be
• 5:55
  kind
• 5:55
  of
• 5:55
  muddy
• 5:56
  because
• 5:57
  you
• 5:57
  can't
• 5:57
  always
• 5:57
  tell
• 5:58
  what
• 5:58
  you're
• 5:58
  looking
• 5:58
  at.
• 5:58
  Is
• 5:58
  this
• 5:59
  a
• 5:59
  primary
• 5:59
  psychotic
• 6:00
  disorder,
• 6:00
  Is
• 6:00
  this
• 6:00
  a
• 6:00
  real
• 6:01
  generalized
• 6:01
  anxiety
• 6:02
  disorder,
• 6:02
  or
• 6:02
  is
• 6:03
  this
• 6:03
  like
• 6:03
  a
• 6:03
  substance
• 6:04
  induced
• 6:04
  mental
• 6:05
  health
• 6:05
  problem?
• 6:06
  We
• 6:06
  can
• 6:06
  only
• 6:06
  tell
• 6:07
  the
• 6:07
  difference
• 6:07
  with
• 6:08
  abstinence,
• 6:08
  typically
• 6:09
  25
• 6:10
  days
• 6:10
  or
• 6:11
  more
• 6:11
  where
• 6:11
  you
• 6:12
  abstain
• 6:12
  from
• 6:12
  the
• 6:12
  substance.
• 6:13
  And
• 6:13
  then
• 6:13
  you
• 6:13
  get
• 6:13
  a
• 6:13
  better
• 6:14
  idea
• 6:14
  of
• 6:15
  whether
• 6:15
  or
• 6:15
  not
• 6:15
  this
• 6:15
  is
• 6:16
  actual
• 6:16
  psycho
• 6:17
  primary
• 6:17
  psychotic
• 6:18
  disorder,
• 6:19
  in
• 6:19
  which
• 6:19
  case
• 6:19
  the
• 6:20
  symptoms
• 6:20
  would
• 6:20
  persist
• 6:21
  and
• 6:21
  be
• 6:22
  equally
• 6:22
  troubling,
• 6:23
  or
• 6:23
  it
• 6:24
  tends
• 6:24
  to
• 6:24
  go
• 6:24
  away
• 6:25
  after
• 6:25
  the
• 6:25
  cessation
• 6:26
  of
• 6:26
  cannabis
• 6:27
  use.
• 6:27
  So
• 6:27
  very
• 6:27
  interesting
• 6:28
  stuff
• 6:28
  here.
• 6:29
  And
• 6:29
  I
• 6:29
  want
• 6:30
  you
• 6:30
  to
• 6:30
  appreciate
• 6:30
  the
• 6:30
  fact
• 6:31
  that
• 6:31
  the
• 6:31
  potency
• 6:32
  absolutely
• 6:32
  matters,
• 6:33
  that
• 6:33
  a
• 6:33
  lot
• 6:33
  of
• 6:33
  these
• 6:33
  symptoms
• 6:34
  are
• 6:34
  dose
• 6:34
  dependent.
• 6:35
  So
• 6:35
  definitely
• 6:36
  get
• 6:36
  your
• 6:36
  feet
• 6:36
  wet
• 6:37
  and
• 6:37
  get
• 6:37
  comfortable
• 6:38
  asking
• 6:38
  the
• 6:38
  potency.
• 6:38
  It's
• 6:39
  not
• 6:39
  enough
• 6:39
  to
• 6:39
  just
• 6:39
  be
• 6:40
  like,
• 6:40
  well,
• 6:40
  do
• 6:40
  you
• 6:40
  use
• 6:41
  cannabis
• 6:42
  products?
• 6:42
  Do
• 6:43
  you?
• 6:43
  You
• 6:43
  gotta
• 6:44
  get
• 6:44
  nitty
• 6:44
  gritty
• 6:44
  and
• 6:44
  talk
• 6:45
  about
• 6:45
  th
• 6:46
  c
• 6:46
  and
• 6:47
  the
• 6:47
  percentage
• 6:48
  and
• 6:48
  encourage
• 6:48
  them.
• 6:48
  Sometimes
• 6:49
  if
• 6:49
  you
• 6:49
  have
• 6:49
  60
• 6:49
  minutes
• 6:50
  for
• 6:50
  an
• 6:50
  intake
• 6:51
  and
• 6:51
  your
• 6:52
  patient's
• 6:52
  just
• 6:52
  in
• 6:53
  their
• 6:53
  bedroom
• 6:53
  and
• 6:54
  they
• 6:54
  have
• 6:54
  their
• 6:55
  cannabis
• 6:55
  products
• 6:56
  laying
• 6:56
  around,
• 6:56
  they
• 6:57
  can
• 6:57
  look
• 6:57
  at
• 6:57
  it
• 6:57
  and
• 6:57
  say,
• 6:58
  hey,
• 6:58
  if
• 6:58
  you
• 6:58
  need
• 6:58
  to
• 6:58
  leave
• 6:59
  our
• 6:59
  appointment
• 7:00
  real
• 7:00
  quick,
• 7:00
  let's
• 7:01
  look
• 7:01
  at
• 7:01
  that.
• 7:01
  Or
• 7:01
  if
• 7:02
  they're
• 7:02
  in
• 7:02
  clinic
• 7:02
  with
• 7:03
  you,
• 7:03
  hey,
• 7:03
  why
• 7:03
  don't
• 7:03
  you
• 7:03
  look
• 7:04
  that
• 7:04
  up
• 7:04
  for
• 7:04
  me
• 7:04
  and
• 7:04
  get
• 7:05
  back
• 7:05
  to
• 7:05
  me
• 7:05
  next
• 7:05
  time?
• 7:05
  Because
• 7:06
  it
• 7:06
  is
• 7:06
  tethered
• 7:07
  to
• 7:07
  very
• 7:07
  specific
• 7:08
  outcomes
• 7:09
  that
• 7:09
  are
• 7:09
  not
• 7:10
  very
• 7:10
  favorable
• 7:10
  either.
• 7:11
  And
• 7:11
  so
• 7:12
  we've
• 7:12
  gotta
• 7:13
  really
• 7:13
  ask
• 7:13
  the
• 7:13
  question.
• 7:13
  Remember
• 7:14
  that
• 7:14
  the
• 7:14
  cannabis
• 7:15
  available
• 7:15
  today
• 7:15
  is
• 7:15
  just
• 7:16
  not
• 7:16
  the
• 7:16
  same
• 7:16
  as
• 7:16
  it
• 7:16
  was
• 7:17
  20
• 7:17
  years
• 7:17
  ago.
• 7:18
  The
• 7:18
  average
• 7:18
  THC
• 7:19
  potency
• 7:19
  has
• 7:19
  doubled
• 7:20
  from
• 7:20
  what
• 7:20
  it
• 7:20
  used
• 7:21
  to
• 7:21
  be.
• 7:22
  So
• 7:22
  this
• 7:22
  is
• 7:22
  not
• 7:23
  really
• 7:23
  helping
• 7:24
  a
• 7:24
  lot
• 7:24
  of
• 7:24
  our
• 7:25
  folks
• 7:25
  who
• 7:25
  are
• 7:25
  already
• 7:25
  struggling
• 7:26
  with
• 7:26
  mental
• 7:26
  health
• 7:27
  problems.
• 7:28
  And
• 7:28
  so,
• 7:28
  you
• 7:28
  know,
• 7:28
  the
• 7:29
  short
• 7:29
  term,
• 7:29
  there's
• 7:29
  some
• 7:29
  euphoria.
• 7:30
  Even
• 7:30
  short
• 7:30
  term.
• 7:31
  Your
• 7:31
  patients
• 7:31
  will
• 7:31
  tell
• 7:32
  you
• 7:32
  it's
• 7:32
  really
• 7:32
  helping
• 7:33
  with
• 7:33
  anxiety.
• 7:33
  But
• 7:34
  again,
• 7:34
  it's
• 7:34
  all
• 7:34
  about
• 7:34
  potency,
• 7:35
  it's
• 7:35
  about
• 7:35
  risk,
• 7:36
  it's
• 7:36
  about
• 7:36
  a
• 7:36
  precipitating
• 7:37
  factor
• 7:37
  that
• 7:38
  can
• 7:38
  make
• 7:38
  things
• 7:38
  worse.
• 7:39
  These
• 7:39
  high
• 7:39
  THC
• 7:40
  concentrations
• 7:41
  are
• 7:41
  certainly
• 7:42
  associated
• 7:42
  with
• 7:43
  worse
• 7:43
  outcomes
• 7:44
  in
• 7:44
  a
• 7:44
  lot
• 7:44
  of
• 7:44
  cases.
• 7:45
  Now,
• 7:46
  my
• 7:46
  third
• 7:47
  pearl
• 7:47
  is
• 7:48
  that
• 7:48
  cannabis
• 7:49
  use
• 7:49
  disorder
• 7:50
  is
• 7:50
  actually
• 7:51
  very
• 7:51
  common.
• 7:51
  It's
• 7:51
  under
• 7:52
  recognized
• 7:52
  and
• 7:52
  under
• 7:53
  treated.
• 7:53
  Cannabis
• 7:54
  use
• 7:54
  disorder
• 7:54
  develops
• 7:55
  in
• 7:55
  about
• 7:55
  29%
• 7:56
  of
• 7:56
  medicinal
• 7:57
  cannabis
• 7:57
  users
• 7:58
  and,
• 7:59
  and
• 7:59
  shows
• 8:00
  really
• 8:00
  strong
• 8:00
  associations
• 8:01
  in
• 8:01
  75%
• 8:02
  of
• 8:02
  high
• 8:03
  potency
• 8:03
  product
• 8:04
  users.
• 8:05
  So
• 8:05
  that's
• 8:06
  a
• 8:06
  big
• 8:06
  deal,
• 8:06
  right?
• 8:07
  29%
• 8:07
  of
• 8:08
  medicinal
• 8:08
  cannabis
• 8:09
  users
• 8:09
  who
• 8:09
  develop
• 8:10
  cannabis
• 8:10
  use
• 8:10
  disorder.
• 8:11
  That
• 8:11
  is
• 8:11
  not
• 8:11
  a
• 8:12
  small
• 8:12
  number.
• 8:13
  Right?
• 8:13
  So
• 8:13
  definitely
• 8:13
  ask
• 8:14
  these
• 8:14
  questions.
• 8:14
  And
• 8:14
  again,
• 8:15
  this
• 8:15
  is
• 8:15
  another
• 8:15
  reason
• 8:16
  you
• 8:16
  want
• 8:16
  to
• 8:16
  focus
• 8:16
  on
• 8:16
  potency,
• 8:17
  because
• 8:17
  there's
• 8:17
  a
• 8:18
  disproportionately
• 8:19
  high
• 8:19
  number
• 8:20
  of
• 8:20
  people
• 8:20
  who
• 8:20
  develop
• 8:21
  cannabis
• 8:22
  use
• 8:22
  disorder
• 8:23
  when
• 8:23
  they're
• 8:23
  using
• 8:24
  a
• 8:24
  high
• 8:24
  potency
• 8:24
  product.
• 8:25
  And
• 8:26
  that,
• 8:26
  my
• 8:26
  friends,
• 8:27
  is
• 8:28
  a
• 8:28
  really
• 8:28
  big
• 8:29
  reason
• 8:29
  to
• 8:29
  ask
• 8:30
  this
• 8:30
  question.
• 8:30
  Culturally,
• 8:31
  this
• 8:31
  is
• 8:31
  just
• 8:32
  so
• 8:32
  difficult,
• 8:32
  right,
• 8:32
  because
• 8:33
  they
• 8:33
  legalized
• 8:34
  cannabis
• 8:34
  or
• 8:35
  decriminalized
• 8:35
  it
• 8:35
  in
• 8:36
  so
• 8:36
  many
• 8:36
  different
• 8:36
  places.
• 8:37
  And
• 8:37
  so
• 8:38
  the
• 8:38
  tendency
• 8:39
  in
• 8:39
  society
• 8:40
  was,
• 8:40
  oh,
• 8:40
  this
• 8:40
  isn't
• 8:41
  so
• 8:41
  bad,
• 8:41
  alcohol
• 8:42
  is
• 8:42
  much
• 8:42
  worse.
• 8:43
  And
• 8:43
  of
• 8:43
  course
• 8:43
  we
• 8:44
  can
• 8:44
  have
• 8:44
  that
• 8:44
  debate,
• 8:45
  but
• 8:45
  absolutely
• 8:46
  this
• 8:46
  is
• 8:46
  problematic.
• 8:47
  And
• 8:47
  the
• 8:48
  high
• 8:48
  concentration
• 8:48
  of
• 8:49
  THC
• 8:50
  is
• 8:50
  at
• 8:50
  the
• 8:51
  very
• 8:51
  best
• 8:51
  case
• 8:52
  scenario
• 8:52
  going
• 8:52
  to
• 8:52
  make
• 8:52
  it
• 8:53
  much
• 8:53
  harder
• 8:53
  to
• 8:53
  understand
• 8:54
  what's
• 8:54
  going
• 8:54
  on
• 8:54
  with
• 8:54
  your
• 8:55
  patient.
• 8:55
  And
• 8:56
  of
• 8:56
  course,
• 8:57
  a
• 8:57
  cannabis
• 8:58
  use
• 8:58
  disorder
• 8:58
  is
• 8:58
  not
• 8:59
  really
• 8:59
  the
• 8:59
  best
• 8:59
  thing
• 9:00
  to
• 9:00
  deal
• 9:00
  with
• 9:01
  given
• 9:01
  the
• 9:01
  fact
• 9:02
  that
• 9:02
  it
• 9:02
  has
• 9:02
  so
• 9:03
  many
• 9:03
  other
• 9:04
  symptomatic
• 9:05
  consequences
• 9:06
  that
• 9:06
  make
• 9:06
  it
• 9:06
  hard
• 9:07
  for
• 9:07
  the
• 9:07
  patient
• 9:07
  to
• 9:07
  get
• 9:07
  better.
• 9:08
  Right?
• 9:08
  Just
• 9:09
  not
• 9:09
  having
• 9:09
  enough
• 9:09
  motivation.
• 10:05
  The
• 10:05
  poor
• 10:05
  executive
• 10:06
  functioning
• 10:07
  alone
• 10:07
  makes
• 10:07
  it
• 10:07
  pretty
• 10:08
  hard
• 10:08
  to
• 10:08
  participate
• 10:08
  in
• 10:09
  psychotherapy,
• 10:10
  which
• 10:10
  we
• 10:10
  know
• 10:11
  is
• 10:11
  a
• 10:11
  very
• 10:11
  rich
• 10:12
  evidence
• 10:12
  based
• 10:12
  way
• 10:13
  to
• 10:13
  combat
• 10:13
  anxiety
• 10:14
  and
• 10:14
  panic
• 10:14
  and
• 10:15
  OCD
• 10:16
  and
• 10:16
  trauma.
• 10:16
  One
• 10:17
  hand
• 10:17
  tied
• 10:17
  behind
• 10:18
  your
• 10:18
  back
• 10:18
  big
• 10:18
  time
• 10:19
  when
• 10:19
  you're
• 10:20
  dealing
• 10:20
  with
• 10:20
  THC
• 10:21
  and
• 10:22
  the
• 10:22
  difficulty
• 10:23
  with
• 10:23
  executive
• 10:24
  functioning.
• 10:25
  Now,
• 10:25
  when
• 10:25
  we
• 10:25
  talk
• 10:26
  about
• 10:26
  cannabis
• 10:26
  use
• 10:26
  disorder
• 10:27
  being
• 10:27
  common
• 10:27
  under
• 10:28
  recognized
• 10:28
  and
• 10:28
  untreated,
• 10:29
  it's
• 10:29
  very
• 10:30
  important
• 10:30
  to
• 10:30
  also
• 10:30
  understand
• 10:32
  that
• 10:32
  the
• 10:32
  highest
• 10:32
  prevalence,
• 10:33
  your
• 10:34
  target
• 10:34
  group,
• 10:34
  if
• 10:35
  you
• 10:35
  will,
• 10:35
  is
• 10:35
  going
• 10:35
  to
• 10:35
  really
• 10:36
  be
• 10:36
  18
• 10:37
  to
• 10:37
  29
• 10:37
  year
• 10:38
  olds,
• 10:38
  about
• 10:38
  7%
• 10:39
  of
• 10:39
  them,
• 10:39
  which
• 10:40
  is
• 10:40
  not
• 10:40
  a
• 10:40
  small
• 10:41
  number
• 10:41
  your
• 10:41
  patients
• 10:41
  add
• 10:42
  up.
• 10:42
  You
• 10:42
  know,
• 10:42
  you
• 10:42
  see
• 10:42
  40
• 10:43
  patients
• 10:43
  a
• 10:43
  week
• 10:43
  or
• 10:43
  30
• 10:44
  patients
• 10:44
  a
• 10:44
  week,
• 10:45
  right?
• 10:45
  After
• 10:46
  three
• 10:46
  weeks,
• 10:47
  you're
• 10:47
  bound
• 10:47
  to
• 10:48
  have
• 10:48
  at
• 10:48
  least
• 10:48
  seven
• 10:48
  or
• 10:49
  eight
• 10:49
  patients
• 10:49
  in
• 10:49
  your
• 10:50
  office
• 10:50
  with
• 10:50
  cannabis
• 10:51
  use
• 10:51
  disorder.
• 10:51
  For
• 10:52
  reasons
• 10:52
  we
• 10:52
  continue
• 10:53
  to
• 10:53
  explain
• 10:53
  on
• 10:53
  this
• 10:54
  podcast,
• 10:54
  you
• 10:54
  will
• 10:55
  understand
• 10:55
  that
• 10:55
  this
• 10:56
  is
• 10:56
  something
• 10:56
  we
• 10:56
  actually
• 10:56
  have
• 10:57
  to
• 10:57
  look
• 10:57
  at.
• 10:57
  It's
• 10:57
  particularly
• 10:58
  vulnerable,
• 10:59
  this
• 10:59
  kind
• 10:59
  of
• 10:59
  thing
• 10:59
  in
• 10:59
  the
• 11:00
  adolescent
• 11:00
  brain.
• 11:01
  It's
• 11:01
  still
• 11:01
  developing
• 11:02
  it's
• 11:02
  hyper
• 11:03
  susceptible
• 11:04
  to
• 11:04
  changes
• 11:05
  in
• 11:05
  the
• 11:06
  way
• 11:06
  that
• 11:06
  these,
• 11:07
  these
• 11:07
  neuro
• 11:08
  circuits
• 11:08
  are
• 11:08
  being
• 11:08
  organized
• 11:09
  and
• 11:09
  modulated
• 11:10
  going
• 11:10
  back
• 11:10
  to
• 11:11
  the
• 11:11
  endocannabinoid
• 11:12
  system.
• 11:12
  Messing
• 11:12
  with
• 11:12
  that
• 11:13
  thermostat
• 11:13
  in
• 11:13
  such
• 11:14
  a
• 11:14
  critically
• 11:14
  vulnerable
• 11:15
  time
• 11:15
  is
• 11:16
  just
• 11:16
  so
• 11:17
  damaging,
• 11:17
  it's
• 11:17
  so
• 11:18
  detrimental.
• 11:19
  We
• 11:19
  see
• 11:19
  that
• 11:19
  folks
• 11:20
  with
• 11:20
  yearly
• 11:21
  use
• 11:21
  of
• 11:21
  cannabis
• 11:22
  have
• 11:22
  about
• 11:22
  a
• 11:22
  3.5%
• 11:23
  prevalence
• 11:24
  of
• 11:24
  cannabis
• 11:24
  use
• 11:24
  disorder.
• 11:25
  Monthly
• 11:26
  use
• 11:26
  jumps
• 11:26
  that
• 11:26
  up
• 11:27
  more
• 11:27
  than
• 11:27
  twofold
• 11:28
  to
• 11:28
  8%
• 11:29
  risk
• 11:29
  of
• 11:30
  cannabis
• 11:30
  use
• 11:30
  disorder.
• 11:31
  And
• 11:31
  then
• 11:31
  weekly
• 11:32
  use,
• 11:32
  five
• 11:32
  days
• 11:33
  a
• 11:33
  week
• 11:33
  or
• 11:34
  more,
• 11:34
  16%
• 11:36
  now
• 11:36
  daily
• 11:37
  use,
• 11:37
  which
• 11:37
  a
• 11:37
  lot
• 11:37
  of
• 11:37
  your
• 11:38
  patients
• 11:38
  will
• 11:38
  tell
• 11:38
  you
• 11:38
  they're
• 11:39
  on
• 11:39
  cannabis
• 11:39
  daily.
• 11:40
  36%
• 11:41
  risk
• 11:41
  of
• 11:41
  developing
• 11:42
  cannabis
• 11:42
  use
• 11:42
  disorder.
• 11:43
  Big,
• 11:44
  big
• 11:44
  problem.
• 11:45
  I
• 11:45
  personally
• 11:46
  find
• 11:46
  that
• 11:46
  some
• 11:47
  of
• 11:47
  my
• 11:47
  patients
• 11:47
  that
• 11:47
  are
• 11:48
  the
• 11:48
  hardest
• 11:48
  to
• 11:48
  treat
• 11:49
  have
• 11:49
  cannabis
• 11:50
  use
• 11:50
  disorder
• 11:50
  or
• 11:50
  extensive
• 11:51
  cannabis
• 11:51
  abuse.
• 11:52
  Some
• 11:52
  of
• 11:52
  them
• 11:52
  are
• 11:53
  the
• 11:53
  hardest
• 11:53
  to
• 11:53
  treat.
• 11:54
  And
• 11:54
  the
• 11:54
  reason
• 11:55
  is
• 11:55
  really
• 11:56
  simple,
• 11:56
  right?
• 11:56
  Let's
• 11:57
  forget
• 11:57
  about
• 11:57
  all
• 11:57
  these
• 11:58
  fancy
• 11:58
  schman
• 11:58
  statistics
• 11:59
  for
• 11:59
  a
• 11:59
  minute.
• 12:00
  But
• 12:00
  the
• 12:00
  reason
• 12:01
  is
• 12:01
  that
• 12:02
  cannabis
• 12:03
  can
• 12:03
  mimic
• 12:04
  so
• 12:04
  many
• 12:04
  things.
• 12:05
  That
• 12:05
  actually
• 12:06
  leads
• 12:06
  into
• 12:07
  my
• 12:07
  last
• 12:07
  pearl,
• 12:08
  which
• 12:08
  I
• 12:08
  love.
• 12:08
  Cannabis
• 12:09
  is
• 12:09
  diagnostic
• 12:10
  mud.
• 12:10
  It's
• 12:11
  challenging
• 12:11
  enough
• 12:12
  to
• 12:12
  have
• 12:12
  someone
• 12:13
  come
• 12:13
  in
• 12:13
  your
• 12:13
  office
• 12:13
  with
• 12:13
  treatment.
• 12:14
  Resistant
• 12:14
  depression,
• 12:15
  trauma,
• 12:15
  or
• 12:16
  you're
• 12:16
  talking
• 12:16
  about
• 12:17
  someone
• 12:17
  with
• 12:17
  a
• 12:17
  lifelong
• 12:18
  history
• 12:19
  of
• 12:19
  struggles
• 12:19
  and
• 12:19
  things
• 12:20
  they
• 12:20
  wish
• 12:20
  could
• 12:20
  be
• 12:20
  better.
• 12:21
  And
• 12:21
  lo
• 12:21
  and
• 12:21
  behold,
• 12:22
  cannabis
• 12:22
  comes
• 12:23
  in
• 12:23
  and
• 12:23
  you
• 12:24
  have
• 12:24
  this
• 12:24
  clear
• 12:24
  river.
• 12:25
  In
• 12:25
  the
• 12:25
  beginning,
• 12:25
  maybe
• 12:25
  it's
• 12:26
  raging,
• 12:26
  maybe
• 12:26
  it's
• 12:26
  hard
• 12:27
  to
• 12:27
  control,
• 12:27
  and
• 12:27
  the
• 12:28
  rapids
• 12:28
  are
• 12:28
  throwing
• 12:29
  you
• 12:29
  to
• 12:29
  the
• 12:29
  banks
• 12:29
  of
• 12:29
  the
• 12:29
  river
• 12:30
  and.
• 12:30
  But
• 12:31
  now
• 12:31
  cannabis
• 12:32
  comes
• 12:32
  in
• 12:32
  and
• 12:32
  it's
• 12:32
  like
• 12:32
  adding
• 12:33
  mud.
• 12:33
  You
• 12:34
  can't
• 12:34
  see
• 12:34
  the
• 12:34
  bottom
• 12:35
  anymore.
• 12:35
  You,
• 12:35
  you
• 12:35
  can
• 12:35
  barely
• 12:36
  see
• 12:36
  the
• 12:36
  way
• 12:36
  the
• 12:36
  river's
• 12:37
  flowing
• 12:37
  and
• 12:37
  what's
• 12:37
  in
• 12:37
  it.
• 12:38
  And
• 12:38
  all
• 12:38
  the
• 12:38
  fish
• 12:38
  are
• 12:39
  gone.
• 12:39
  You
• 12:39
  just
• 12:39
  can't
• 12:40
  see
• 12:40
  much
• 12:40
  anymore
• 12:41
  because
• 12:41
  it
• 12:41
  mimics
• 12:42
  so
• 12:42
  many
• 12:42
  different
• 12:42
  things.
• 12:43
  Cannabis
• 12:44
  intoxication
• 12:45
  or
• 12:45
  cannabis
• 12:45
  use
• 12:46
  every
• 12:46
  night
• 12:47
  or
• 12:47
  high
• 12:47
  dose
• 12:48
  THC
• 12:48
  dose
• 12:49
  dependent
• 12:49
  risk
• 12:49
  for
• 12:50
  psychosis.
• 12:50
  So
• 12:50
  it's
• 12:50
  like,
• 12:51
  am
• 12:51
  I
• 12:51
  looking
• 12:51
  at
• 12:51
  primary
• 12:52
  psychotic
• 12:52
  disorder
• 12:53
  or
• 12:53
  am
• 12:53
  I
• 12:53
  looking
• 12:53
  at
• 12:54
  something
• 12:54
  that's
• 12:54
  cannabis
• 12:55
  ind.
• 12:56
  Cannabis
• 12:56
  use
• 12:56
  over
• 12:57
  time
• 12:57
  starts
• 12:58
  to
• 12:58
  actually
• 12:58
  make
• 12:58
  it
• 12:59
  harder
• 12:59
  to
• 12:59
  synthesize
• 13:00
  dopamine.
• 13:01
  Your
• 13:01
  actual
• 13:02
  endogenous
• 13:03
  dopamine
• 13:03
  becomes
• 13:04
  harder
• 13:04
  to
• 13:04
  synthesize.
• 13:05
  Your
• 13:05
  dopamine
• 13:06
  transporters
• 13:07
  get
• 13:07
  dysregulated.
• 13:08
  So
• 13:08
  it's
• 13:08
  like,
• 13:08
  am
• 13:08
  I
• 13:08
  looking
• 13:09
  at
• 13:09
  depression
• 13:09
  or
• 13:09
  a
• 13:10
  dopamine
• 13:10
  system
• 13:11
  that's
• 13:11
  all
• 13:11
  disfigured
• 13:12
  now?
• 13:12
  It's
• 13:13
  hard
• 13:13
  for
• 13:13
  me
• 13:13
  to
• 13:13
  know
• 13:13
  that
• 13:14
  because,
• 13:14
  you
• 13:15
  know,
• 13:15
  if
• 13:15
  you're
• 13:15
  not
• 13:15
  asking
• 13:16
  the
• 13:16
  questions
• 13:16
  and
• 13:17
  everybody's
• 13:17
  confused,
• 13:18
  we
• 13:18
  don't
• 13:18
  know.
• 13:18
  It's
• 13:18
  like,
• 13:18
  well,
• 13:19
  do
• 13:19
  I
• 13:19
  add
• 13:19
  an
• 13:19
  SSRI
• 13:20
  or
• 13:20
  do
• 13:20
  I
• 13:21
  have
• 13:21
  this
• 13:21
  patient
• 13:22
  wait
• 13:22
  25
• 13:22
  to
• 13:23
  30
• 13:23
  days,
• 13:23
  and
• 13:23
  they're
• 13:24
  miserable
• 13:24
  doing
• 13:24
  it
• 13:25
  and
• 13:25
  just
• 13:25
  clear
• 13:26
  out
• 13:26
  cannabis?
• 13:26
  What
• 13:27
  if
• 13:27
  I
• 13:27
  can't
• 13:27
  clear
• 13:27
  out
• 13:28
  cannabis?
• 13:28
  What
• 13:28
  if
• 13:28
  they're
• 13:28
  not
• 13:29
  motivationally
• 13:29
  inclined
• 13:30
  to
• 13:30
  reduce
• 13:31
  their
• 13:31
  cannabis
• 13:31
  use?
• 13:32
  Am
• 13:32
  I
• 13:32
  looking
• 13:32
  at
• 13:32
  a
• 13:32
  cannabis
• 13:33
  use
• 13:33
  disorder?
• 13:34
  Am
• 13:34
  I
• 13:34
  looking
• 13:34
  at
• 13:34
  depression?
• 13:35
  That
• 13:35
  makes
• 13:35
  it
• 13:35
  even
• 13:36
  harder
• 13:36
  because
• 13:36
  patients
• 13:37
  will
• 13:37
  often
• 13:37
  tell
• 13:38
  you,
• 13:38
  I've
• 13:38
  been
• 13:38
  depressed
• 13:39
  my
• 13:39
  whole
• 13:39
  life.
• 13:39
  And
• 13:39
  I've
• 13:39
  also
• 13:40
  used
• 13:40
  cannabis
• 13:41
  for
• 13:41
  the
• 13:41
  last
• 13:41
  eight
• 13:42
  years.
• 13:42
  So,
• 13:42
  again,
• 13:42
  difficult
• 13:43
  diagnostically.
• 13:44
  And
• 13:44
  we
• 13:44
  all
• 13:44
  know
• 13:45
  if
• 13:45
  you
• 13:45
  don't
• 13:45
  have
• 13:45
  a
• 13:45
  great
• 13:46
  diagnosis,
• 13:47
  well,
• 13:47
  then
• 13:47
  it's
• 13:47
  not
• 13:48
  as
• 13:48
  easy
• 13:48
  to
• 13:48
  go
• 13:49
  down
• 13:49
  a
• 13:49
  treatment
• 13:49
  algorithm
• 13:50
  and.
• 13:50
  And
• 13:50
  give
• 13:51
  your
• 13:51
  patient
• 13:51
  the
• 13:51
  most
• 13:51
  bang
• 13:52
  for
• 13:52
  their
• 13:52
  buck.
• 13:53
  They
• 13:53
  have
• 13:53
  deficits
• 13:53
  in
• 13:54
  attention
• 13:54
  and
• 13:54
  executive
• 13:55
  function.
• 13:55
  Well,
• 13:55
  am
• 13:55
  I
• 13:56
  looking
• 13:56
  at
• 13:56
  adhd
• 13:57
  or
• 13:57
  am
• 13:57
  I
• 13:57
  looking
• 13:57
  at
• 13:58
  cannabis
• 13:58
  use?
• 13:58
  Oh,
• 13:59
  I
• 13:59
  started,
• 13:59
  you
• 14:00
  know,
• 14:00
  smoking
• 14:01
  high
• 14:01
  potency
• 14:02
  THC
• 14:02
  at
• 14:02
  age
• 14:03
  14.
• 14:03
  Well,
• 14:04
  okay,
• 14:04
  now
• 14:04
  I
• 14:04
  really
• 14:05
  have
• 14:05
  no
• 14:05
  idea.
• 14:05
  Is
• 14:05
  this
• 14:06
  adhd?
• 14:06
  Is
• 14:07
  this
• 14:07
  cannabis?
• 14:08
  Hard
• 14:08
  to
• 14:08
  tell.
• 14:09
  Hard
• 14:09
  to
• 14:09
  pay
• 14:09
  attention
• 14:10
  for
• 14:10
  both
• 14:11
  of
• 14:11
  those
• 14:11
  conditions.
• 14:11
  Poor
• 14:12
  impulse
• 14:12
  control,
• 14:13
  the
• 14:13
  processing
• 14:14
  speed,
• 14:14
  working
• 14:14
  memory.
• 14:15
  There's
• 14:15
  a
• 14:15
  lot
• 14:15
  of
• 14:16
  ways
• 14:16
  that
• 14:16
  ADHD
• 14:17
  and
• 14:17
  cannabis
• 14:18
  use
• 14:18
  looks
• 14:19
  similar.
• 14:20
  So
• 14:20
  you
• 14:20
  want
• 14:20
  to
• 14:20
  encourage
• 14:21
  abstinence
• 14:21
  if
• 14:21
  it's
• 14:22
  possible
• 14:22
  for
• 14:22
  at
• 14:22
  least
• 14:23
  25
• 14:23
  days
• 14:24
  to
• 14:24
  see
• 14:24
  if
• 14:24
  those
• 14:25
  ADHD
• 14:25
  symptoms
• 14:26
  persist
• 14:26
  regardless
• 14:27
  of
• 14:27
  cannabis
• 14:27
  use.
• 14:28
  But
• 14:28
  it
• 14:29
  is
• 14:29
  also
• 14:29
  easier
• 14:30
  said
• 14:30
  than
• 14:30
  done.
• 14:31
  Anxiety
• 14:32
  disorders.
• 14:33
  We
• 14:33
  talked
• 14:33
  about
• 14:33
  high
• 14:34
  potency
• 14:34
  THC
• 14:35
  greater
• 14:36
  than
• 14:36
  10%.
• 14:37
  GAD
• 14:37
  rates
• 14:38
  increased
• 14:38
  from
• 14:38
  11.6
• 14:39
  to
• 14:40
  19.1%.
• 14:41
  That's
• 14:41
  really
• 14:42
  significant,
• 14:42
  right?
• 14:43
  That's
• 14:43
  like
• 14:43
  a
• 14:43
  50%
• 14:44
  increase
• 14:44
  in
• 14:45
  generalized
• 14:45
  anxiety
• 14:46
  disorder
• 14:46
  presentations
• 14:47
  because
• 14:48
  of
• 14:48
  high
• 14:48
  potency
• 14:49
  cannabis
• 14:50
  use.
• 14:50
  And
• 14:51
  it
• 14:51
  can
• 14:51
  acutely
• 14:51
  produce
• 14:52
  anxiety
• 14:52
  and
• 14:52
  panic
• 14:53
  like
• 14:53
  symptoms.
• 14:53
  So
• 14:53
  it's
• 14:54
  like,
• 14:54
  am
• 14:54
  I
• 14:54
  looking
• 14:54
  at
• 14:54
  a
• 14:54
  panic
• 14:55
  attack
• 14:55
  or
• 14:55
  just
• 14:56
  THC
• 14:57
  use
• 14:57
  that
• 14:57
  is
• 14:57
  chronic
• 14:58
  and
• 14:58
  high
• 14:59
  potency?
• 15:00
  Well,
• 15:00
  it's
• 15:00
  hard
• 15:01
  to
• 15:01
  say,
• 15:01
  right?
• 15:01
  You
• 15:02
  don't
• 15:02
  want
• 15:02
  to
• 15:02
  start
• 15:02
  polypharmacy.
• 15:03
  You
• 15:03
  don't
• 15:03
  want
• 15:04
  your
• 15:04
  patients
• 15:04
  to
• 15:04
  be
• 15:04
  on
• 15:04
  19
• 15:05
  different
• 15:05
  meds
• 15:05
  while
• 15:06
  you
• 15:06
  figure
• 15:06
  it
• 15:06
  out
• 15:06
  with
• 15:07
  their
• 15:07
  accompanying
• 15:07
  side
• 15:08
  effects.
• 15:09
  God
• 15:09
  forbid
• 15:09
  you
• 15:10
  add
• 15:10
  Zyprexa.
• 15:10
  The
• 15:11
  patient
• 15:11
  gains
• 15:11
  30
• 15:12
  pounds,
• 15:12
  and
• 15:13
  they
• 15:13
  have
• 15:13
  all
• 15:14
  kinds
• 15:14
  of
• 15:14
  movement
• 15:14
  problems
• 15:16
  now,
• 15:16
  and
• 15:16
  their
• 15:17
  blood
• 15:17
  sugar's
• 15:17
  through
• 15:18
  the
• 15:18
  roof,
• 15:18
  and
• 15:18
  your
• 15:19
  cholesterol
• 15:19
  just
• 15:19
  went
• 15:20
  up
• 15:20
  900
• 15:20
  points
• 15:21
  and,
• 15:21
  oh,
• 15:21
  all
• 15:22
  you
• 15:22
  had
• 15:22
  to
• 15:22
  do
• 15:22
  is
• 15:22
  talk
• 15:23
  a
• 15:23
  little
• 15:23
  bit
• 15:23
  more
• 15:23
  about
• 15:23
  cannabis.
• 15:24
  Right?
• 15:24
  So
• 15:25
  this
• 15:25
  is
• 15:25
  the
• 15:26
  challenge
• 15:26
  that
• 15:27
  we
• 15:27
  are
• 15:27
  presented
• 15:27
  with.
• 15:28
  Bipolar,
• 15:29
  Right.
• 15:29
  It's
• 15:29
  another
• 15:29
  muddy
• 15:30
  diagnostic,
• 15:31
  because
• 15:31
  cannabis
• 15:32
  use
• 15:32
  disorder
• 15:32
  is
• 15:33
  associated
• 15:33
  with
• 15:33
  a
• 15:34
  increase
• 15:34
  of
• 15:35
  developing
• 15:35
  bipolar
• 15:36
  disorder
• 15:36
  by
• 15:37
  2.5
• 15:37
  to
• 15:37
  three
• 15:38
  fold.
• 15:38
  That's
• 15:39
  significant.
• 15:39
  Particularly
• 15:40
  the
• 15:40
  psychotic
• 15:41
  form
• 15:41
  of
• 15:41
  bipolar
• 15:42
  disorder
• 15:42
  with
• 15:42
  a
• 15:43
  hazard
• 15:43
  ratio
• 15:43
  of
• 15:44
  four.
• 15:44
  Right.
• 15:45
  So
• 15:45
  that's
• 15:46
  also
• 15:46
  very
• 15:46
  problematic
• 15:47
  because
• 15:47
  it's
• 15:48
  like,
• 15:48
  well,
• 15:48
  is
• 15:48
  my
• 15:48
  Patient
• 15:49
  irritable
• 15:49
  and
• 15:50
  labile
• 15:50
  because
• 15:50
  of
• 15:51
  all
• 15:51
  of
• 15:51
  the
• 15:51
  dysregulation
• 15:52
  that's
• 15:52
  taking
• 15:53
  place
• 15:53
  in
• 15:53
  their
• 15:53
  dopaminergic
• 15:55
  circuits.
• 15:55
  And
• 15:56
  the
• 15:56
  excitatory
• 15:57
  neurotransmitters
• 15:58
  now
• 15:58
  are
• 15:58
  more
• 15:58
  abundant
• 15:59
  because
• 15:59
  there
• 16:00
  isn't
• 16:00
  this
• 16:00
  retrograde
• 16:01
  inhibition
• 16:01
  that
• 16:02
  cools
• 16:02
  down
• 16:02
  the
• 16:02
  glutamate
• 16:03
  or
• 16:03
  some
• 16:03
  of
• 16:03
  these
• 16:03
  excitatory
• 16:04
  circuits
• 16:05
  and
• 16:05
  neurotransmitters.
• 16:06
  So
• 16:06
  again,
• 16:07
  you
• 16:07
  can
• 16:07
  now
• 16:07
  come
• 16:08
  full
• 16:08
  circle
• 16:08
  with
• 16:08
  this
• 16:09
  and
• 16:09
  have
• 16:10
  a
• 16:10
  full
• 16:10
  appreciation
• 16:11
  for
• 16:11
  the
• 16:11
  fact
• 16:11
  that
• 16:11
  dysregulating
• 16:12
  the
• 16:13
  endocannabinoid
• 16:14
  system,
• 16:15
  downrate,
• 16:16
  downregulating
• 16:17
  dopamine,
• 16:17
  messing
• 16:18
  with
• 16:18
  the
• 16:18
  reward
• 16:19
  circuits,
• 16:20
  all
• 16:20
  of
• 16:20
  that
• 16:20
  is
• 16:21
  going
• 16:21
  to
• 16:21
  make
• 16:21
  this
• 16:21
  indistinguishable
• 16:23
  from
• 16:23
  a
• 16:23
  depressive
• 16:23
  disorder
• 16:24
  and
• 16:24
  a
• 16:24
  cannabis
• 16:24
  use
• 16:25
  disorder.
• 16:25
  It
• 16:25
  just
• 16:25
  gets
• 16:25
  really
• 16:26
  difficult.
• 16:27
  That's
• 16:27
  something
• 16:27
  we
• 16:28
  really
• 16:28
  want
• 16:29
  to
• 16:30
  pay
• 16:30
  attention
• 16:30
  to.
• 16:31
  The
• 16:31
  impact
• 16:31
  on
• 16:32
  psychosis
• 16:32
  with
• 16:32
  high
• 16:33
  potency.
• 16:33
  THC
• 16:34
  is
• 16:34
  very
• 16:34
  significant.
• 16:35
  The
• 16:35
  psychotic
• 16:36
  like
• 16:36
  experience
• 16:36
  increased
• 16:37
  from
• 16:37
  7%
• 16:38
  to
• 16:38
  12%
• 16:39
  when
• 16:39
  using
• 16:40
  high
• 16:40
  THC
• 16:41
  products.
• 16:42
  Usually
• 16:43
  in
• 16:43
  folks
• 16:43
  who
• 16:43
  are
• 16:43
  susceptible
• 16:44
  with
• 16:44
  a
• 16:44
  family
• 16:45
  history.
• 16:45
  But
• 16:45
  again,
• 16:45
  making
• 16:46
  your
• 16:46
  life
• 16:46
  very
• 16:47
  difficult.
• 16:48
  And
• 16:49
  that's
• 16:49
  really
• 16:49
  all
• 16:50
  I
• 16:50
  have
• 16:50
  and
• 16:50
  I
• 16:50
  hope
• 16:51
  you
• 16:51
  enjoyed
• 16:51
  that.
• 16:51
  I
• 16:51
  feel
• 16:51
  like
• 16:52
  that
• 16:52
  packed
• 16:52
  a
• 16:53
  punch
• 16:53
  for
• 16:53
  me.
• 16:53
  Going
• 16:54
  back
• 16:54
  to
• 16:54
  the
• 16:54
  evidence
• 16:55
  and
• 16:55
  looking
• 16:55
  at
• 16:55
  this
• 16:55
  stuff
• 16:56
  like
• 16:56
  I
• 16:56
  always
• 16:57
  do
• 16:57
  at
• 16:57
  the
• 16:57
  end
• 16:57
  of
• 16:57
  these
• 16:58
  podcasts,
• 16:58
  I
• 16:59
  like
• 16:59
  to
• 16:59
  just
• 16:59
  have
• 16:59
  a
• 16:59
  real
• 17:00
  conversation
• 17:00
  with
• 17:01
  you
• 17:01
  guys
• 17:01
  and
• 17:01
  say
• 17:02
  you
• 17:02
  want
• 17:02
  to
• 17:02
  ask
• 17:03
  the
• 17:03
  questions
• 17:03
  about
• 17:04
  the
• 17:04
  potency.
• 17:04
  You
• 17:04
  want
• 17:05
  to
• 17:05
  educate
• 17:05
  your
• 17:05
  patients
• 17:06
  about
• 17:06
  this
• 17:06
  too.
• 17:06
  There
• 17:07
  is
• 17:07
  a
• 17:07
  giant
• 17:08
  disconnect
• 17:09
  right
• 17:09
  now
• 17:10
  between
• 17:10
  how
• 17:11
  society
• 17:11
  is
• 17:11
  perceiving
• 17:12
  cannabis
• 17:13
  use
• 17:13
  and
• 17:14
  how
• 17:14
  it
• 17:15
  plays
• 17:15
  out
• 17:15
  in
• 17:15
  their
• 17:15
  mental
• 17:15
  health.
• 17:16
  You
• 17:16
  have
• 17:16
  this
• 17:16
  tsunami
• 17:17
  of
• 17:17
  people
• 17:18
  who
• 17:18
  really
• 17:18
  want
• 17:18
  to
• 17:19
  tackle
• 17:19
  their
• 17:19
  mental
• 17:19
  health
• 17:19
  for
• 17:20
  the
• 17:20
  first
• 17:20
  time.
• 17:20
  And
• 17:21
  I
• 17:21
  don't
• 17:21
  want
• 17:21
  to
• 17:21
  speak
• 17:21
  for
• 17:22
  them,
• 17:22
  but
• 17:22
  I
• 17:22
  feel
• 17:22
  as
• 17:23
  though
• 17:23
  high
• 17:24
  number
• 17:24
  of
• 17:24
  them,
• 17:24
  a
• 17:24
  high
• 17:25
  percentage
• 17:25
  of
• 17:25
  them
• 17:25
  also
• 17:26
  don't
• 17:26
  seem
• 17:26
  to
• 17:27
  interpret
• 17:27
  cannabis
• 17:28
  as
• 17:28
  that
• 17:28
  detrimental.
• 17:30
  Lo
• 17:30
  and
• 17:30
  behold,
• 17:30
  my
• 17:31
  friends,
• 17:31
  I
• 17:31
  have
• 17:32
  a
• 17:32
  really
• 17:32
  good
• 17:32
  go
• 17:32
  by.
• 17:32
  If
• 17:33
  you
• 17:33
  become
• 17:33
  a
• 17:33
  Patreon
• 17:34
  member
• 17:34
  that
• 17:34
  I
• 17:35
  created
• 17:35
  for
• 17:35
  you
• 17:35
  to
• 17:36
  have
• 17:36
  a
• 17:36
  discussion
• 17:36
  with
• 17:36
  your
• 17:37
  patients
• 17:37
  to
• 17:38
  facilitate
• 17:39
  the
• 17:39
  conversation
• 17:40
  about
• 17:40
  how
• 17:41
  this
• 17:41
  might
• 17:41
  not
• 17:41
  necessarily
• 17:42
  be
• 17:42
  in
• 17:42
  their
• 17:42
  interest,
• 17:42
  I
• 17:43
  highly
• 17:43
  recommend
• 17:44
  you
• 17:44
  go
• 17:44
  in
• 17:44
  the
• 17:44
  show
• 17:44
  notes,
• 17:45
  you
• 17:45
  become
• 17:45
  Patreon
• 17:46
  members.
• 17:46
  We
• 17:46
  lowered
• 17:47
  the
• 17:47
  price
• 17:47
  actually
• 17:48
  just
• 17:48
  $3
• 17:48
  a
• 17:49
  month.
• 17:49
  You
• 17:49
  have
• 17:49
  access
• 17:49
  to
• 17:49
  all
• 17:50
  these
• 17:50
  slide
• 17:50
  decks,
• 17:51
  beautiful
• 17:51
  slideshows.
• 17:52
  You
• 17:52
  can
• 17:52
  join
• 17:53
  street
• 17:53
  tips
• 17:53
  where
• 17:54
  you
• 17:54
  just
• 17:54
  get
• 17:54
  straight
• 17:54
  up
• 17:55
  bullet
• 17:55
  point
• 17:56
  tips.
• 17:57
  Every
• 17:57
  week
• 17:57
  they're
• 17:58
  updated
• 17:58
  about
• 17:58
  how
• 17:59
  to
• 17:59
  practice
• 17:59
  better,
• 17:59
  what
• 18:00
  to
• 18:00
  look
• 18:00
  for.
• 18:01
  And
• 18:01
  so
• 18:01
  yeah,
• 18:01
  you
• 18:01
  can
• 18:02
  get
• 18:02
  this
• 18:02
  cannabis
• 18:02
  go
• 18:03
  by
• 18:03
  things
• 18:03
  that
• 18:03
  you
• 18:04
  can
• 18:04
  actually,
• 18:04
  you
• 18:04
  can
• 18:04
  print
• 18:05
  it
• 18:05
  out,
• 18:05
  look
• 18:05
  at
• 18:05
  it,
• 18:06
  have
• 18:06
  a
• 18:06
  discussion
• 18:07
  every
• 18:07
  time
• 18:07
  a
• 18:07
  patient's
• 18:07
  using
• 18:08
  THC
• 18:08
  so
• 18:09
  that
• 18:09
  you
• 18:09
  have
• 18:09
  a
• 18:09
  richer,
• 18:10
  more
• 18:10
  comprehensive
• 18:11
  conversation
• 18:12
  about
• 18:12
  this
• 18:12
  stuff
• 18:13
  that
• 18:13
  might
• 18:13
  serve
• 18:13
  as
• 18:14
  motivation
• 18:14
  for
• 18:14
  them
• 18:15
  to
• 18:15
  go,
• 18:15
  wait
• 18:15
  a
• 18:15
  minute.
• 18:16
  This
• 18:16
  doesn't
• 18:16
  really
• 18:16
  serve
• 18:17
  my
• 18:17
  goals.
• 18:17
  Maybe
• 18:17
  I
• 18:18
  need
• 18:18
  to
• 18:18
  stop.
• 18:19
  So
• 18:19
  I'm
• 18:19
  going
• 18:19
  to
• 18:19
  include
• 18:19
  that
• 18:20
  again.
• 18:20
  Go
• 18:20
  to
• 18:21
  the
• 18:21
  Show
• 18:21
  Notes,
• 18:21
  become
• 18:22
  Patreon
• 18:22
  members
• 18:22
  and
• 18:23
  you
• 18:23
  will
• 18:23
  have
• 18:23
  access
• 18:24
  to
• 18:24
  that.
• 18:24
  I
• 18:24
  would
• 18:25
  highly
• 18:25
  appreciate
• 18:26
  your
• 18:26
  support
• 18:26
  if
• 18:26
  you
• 18:27
  became
• 18:27
  members
• 18:27
  and
• 18:28
  I
• 18:28
  appreciate
• 18:28
  each
• 18:28
  and
• 18:28
  every
• 18:29
  one
• 18:29
  of
• 18:29
  you
• 18:29
  for
• 18:29
  being
• 18:29
  loyal
• 18:30
  fans
• 18:30
  of
• 18:30
  our
• 18:30
  podcast.
• 18:31
  We're
• 18:31
  growing
• 18:31
  fast.
• 18:32
  There's
• 18:32
  a
• 18:32
  lot
• 18:32
  of
• 18:32
  word
• 18:32
  of
• 18:33
  mouth
• 18:33
  spreading
• 18:34
  to
• 18:34
  different
• 18:34
  countries
• 18:35
  now.
• 18:35
  I
• 18:36
  think
• 18:36
  different
• 18:36
  NP
• 18:36
  schools
• 18:37
  out
• 18:37
  there
• 18:37
  are
• 18:37
  sharing
• 18:38
  this
• 18:38
  resource
• 18:38
  and
• 18:38
  that's
• 18:39
  always
• 18:39
  a
• 18:39
  beautiful
• 18:39
  thing.
• 18:40
  Go
• 18:40
  to
• 18:40
  the
• 18:40
  Show
• 18:40
  Notes
• 18:41
  and
• 18:41
  email
• 18:41
  me
• 18:42
  as
• 18:42
  well.
• 18:42
  Ask
• 18:42
  for
• 18:42
  questions.
• 18:43
  When
• 18:43
  you
• 18:43
  become
• 18:43
  a
• 18:44
  Patreon
• 18:44
  member,
• 18:45
  you
• 18:45
  can
• 18:45
  also
• 18:45
  suggest
• 18:45
  new
• 18:46
  episodes
• 18:47
  and
• 18:47
  things
• 18:47
  that
• 18:47
  you
• 18:47
  want
• 18:47
  to
• 18:48
  go
• 18:48
  over
• 18:48
  and
• 18:48
  that's
• 18:48
  always
• 18:49
  really
• 18:49
  fun.
• 18:49
  Creating
• 18:50
  a
• 18:50
  community
• 18:50
  together
• 18:51
  is
• 18:51
  really
• 18:51
  cool.
• 18:52
  My
• 18:52
  dream,
• 18:53
  my
• 18:53
  vision
• 18:54
  for
• 18:54
  this
• 18:54
  podcast
• 18:54
  is
• 18:55
  that
• 18:55
  we
• 18:55
  work
• 18:55
  together
• 18:55
  on
• 18:56
  Patreon
• 18:56
  to
• 18:56
  create
• 18:57
  this
• 18:57
  amazing
• 18:57
  study
• 18:58
  hall,
• 18:58
  this
• 18:58
  one
• 18:58
  stop
• 18:59
  shop
• 18:59
  for
• 18:59
  students
• 19:00
  that
• 19:00
  are
• 19:00
  studying
• 19:01
  psychiatry
• 19:01
  to
• 19:01
  really
• 19:02
  put
• 19:02
  all
• 19:02
  this
• 19:02
  stuff
• 19:02
  together
• 19:03
  right?
• 19:04
  The
• 19:04
  Maoi
• 19:05
  diet,
• 19:06
  the
• 19:06
  endocannabinoid
• 19:07
  system,
• 19:08
  the
• 19:08
  antipsychotic
• 19:09
  switching,
• 19:10
  all
• 19:10
  this.
• 19:10
  These
• 19:11
  clever
• 19:11
  good
• 19:11
  visual
• 19:12
  go
• 19:12
  bys
• 19:13
  to
• 19:13
  make
• 19:13
  learning
• 19:13
  more
• 19:14
  fun
• 19:14
  and
• 19:14
  easier.
• 19:15
  That
• 19:15
  would
• 19:15
  be
• 19:15
  incredible.
• 19:16
  Thank
• 19:16
  you
• 19:16
  to
• 19:16
  each
• 19:16
  and
• 19:17
  every
• 19:17
  one
• 19:17
  of
• 19:17
  you.
• 19:17
  See
• 19:17
  you
• 19:17
  next
• 19:18
  time
• 19:18
  on
• 19:18
  Pearls
• 19:19
  and
• 19:19
  Prep.
• 19:20
  Take
• 19:20
  care.
• 19:20
  Bye
• 19:20
  bye.