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Depression Subtypes: Is It Cognitive or Biological?
Is depression a cognitive pattern you can think your way out of, or a biological condition that needs medication? The answer is both — and neither. This episode explores the history of reactive vs. endogenous depression, the DSM specifiers like melancholic and atypical features, and the emerging research on biotypes defined by brain circuitry and biomarkers. We break down the HPA axis, the dexamethasone suppression test, and why the psychological vs. biological distinction is a false dichotomy. For anyone who's wondered why therapy works for some people but not others — or whether their own…
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