What Happens to Your Body When You Don_t Sleep_ Psychology of Exhaustion
After seventeen hours without sleep, your reaction time matches someone with a blood alcohol level of 0.05 percent. After twenty-four hours, it matches 0.10 percent. After forty-eight hours, your brain begins to eat itself. This is not a metaphor.The glymphatic system, which clears toxic waste from the brain, only activates during deep sleep. Without it, amyloid beta and tau proteins accumulate, the same proteins linked to Alzheimer's disease. The prefrontal cortex, responsible for decision-making and impulse control, shuts down first. The amygdala, responsible for emotional reactions…
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