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Why Antidepressants Take Weeks to Work: The Science of Lag
Why do antidepressants take weeks to work when they alter brain chemistry almost instantly? This episode dives into the "neuroplasticity hypothesis," explaining how SSRIs act less like a light switch and more like a fertilizer for the brain. We explore the role of BDNF in repairing neural connections, the biological struggle of receptor downregulation, and why serotonin’s massive presence in the gut leads to common initial side effects. It is a deep look at the high-stakes waiting game of mental health recovery and the physical architecture of the human brain. Episode 840 —…
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