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Pearl of the Week: What Is the Only Transdermal Antidepressant?

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.”Be the second on Patreon:👉 https://www.patreon.com/PearlsandPrepThis week’s Pearl of the Week dives into one of psychiatry’s most overlooked breakthroughs: the only transdermal antidepressant the FDA has ever approved. Why did this one medication earn a category all its own? What makes its delivery system different? And how did it manage to bypass the infamous tyramine diet—but only at one very specific dose?In this episode, we explore the surprising science behind a patch that quietly…

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