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Why SSRIs Can Make You Drenched at 3 AM
Ten to fifteen percent of SSRI users experience excessive sweating or heat intolerance — and it's a leading reason people quit their medication. This episode unpacks the hypothalamic mechanisms behind the phenomenon, from 5-HT2A receptor activation to anticholinergic rebound. We break down which SSRIs are worst (paroxetine) and best (escitalopram), why genetic metabolizer status matters, and how to differentiate thermoregulatory sweating from emotional sweating. If you've ever woken up drenched and wondered why, this episode is for you. Episode 2912 — myweirdprompts.com/n/2912 (permanent…
The skinny
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