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Rebooting the Brain: The Science of ECT and TMS
When standard antidepressants like SSRIs aren't enough, where does psychiatry turn? In this episode, Herman and Corn Poppleberry tackle the heavy but fascinating world of treatment-resistant depression (TRD). They trace the history of electroconvulsive therapy from its dark origins in 1930s slaughterhouses to its modern-day application as a refined, life-saving clinical procedure. By exploring the mechanisms of "controlled reboots," Brain-Derived Neurotrophic Factor (BDNF), and the "snow globe" effect on the brain's Default Mode Network, the duo explains why inducing a seizure can sometimes…
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